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Calmodulin, Porcine, Fluorescein |产品详情|进口榴莲视频免费观看采购网





    榴莲视频下载地址入口,8008APP幸福宝榴莲,榴莲视频免费观看,榴莲视频污污污下载

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    上海榴莲视频下载地址入口生物科技公司
    Tel:400-968-7988    021-33779008
    Calmodulin, Porcine, Fluorescein
    品牌:AG Scientific
    货号:
    规格:100 ug
    货期:

    Appearance:LyophilizedPurity:98%

    商品详情 参考文献 相关资料

    FITC labeled mammalian calmodulin.Calmodulin (CaM) is an intracellular calcium receptor found ubiquitously in eukaryotes. It is capable of regulating biological activities of many cellular proteins and transmembrane ion transporters mainly in a Ca2+-dependent manner. When the intracellular calcium level rises to 10-5 M, four Ca2+ ions bind to calmodulin, and this Ca2+-calmodulin complex binds the target proteins, initiating various signaling cascades. CaM functions as an intracellular calcium ion bridge to mediate cellular reactions and responds appropriately to calcium ion concentration. In Alzheimer's disease (AD), irregular calcium homeostasis seems to trigger CaM and its binding proteins, to enhance plaque formation and neurofibrillary degeneration, which results in cell death.In Parkinson's disease (PD), Calmodulin has been found to interact, in a calcium-dependent manner, with Alpha-Synuclein, which is associated with the progression of PD. CaM was identified as one of the synuclein-interacting proteins that regulate synuclein conformation.

     

    Additional Information

    Product #C-1435
    AppearanceLyophilized
    Purity98%
    SolubilityCompletely soluble in water. Clear and colorless at 1mg/mL
    Storage Temp-20°C

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