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EDAC or WSC is a versatile modern coupling agent. It is an easily handled solid with high solubility in water (200gl-1) and organic solvents such as dichloromethane, tetrahydrofuran and dimethylformamide. EDC is often preferred to dicyclohexycarbodiimide (DCC) in peptide synthesis because of its ease of handling and the enhanced solubility of EDC and the urea by-product formed during the coupling reaction. The urea by-product is readily soluble in water and can easily be removed by extraction whereas the DCC by-product, dicyclohexylurea, is usually removed by multiple filtrations.

Additional Information

Synonyms	EDC, Water Soluble Carbodiimide, WSC, N-Ethyl-N′-(3-dimethylaminopropyl)carbodiimide hydrochloride, EDAC, EDC hydrochloride, WSC hydrochloride, 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide HCl
Product #	E-2042
CAS #	25952-53-8
Chemical Name	1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide HCl
Formula	C8H17N3 .HCl
MW	191.7
Appearance	White to off-white Powder
Purity	98%
Solubility	Soluble in water (>200 mg/ml), ethanol, DMF, alcohol, and methanol.
Melting Point	112.1 -112.3°C
Storage Temp	-20°C
Use	EDAC is a versatile modern coupling agent

Additional Information

MDL Number	MFCD00012503
ChemACX	X1010061-7
InChI	InChI=1S/C8H17N3.ClH/c1-4-9-8-10-6-5-7-11(2)3;/h4-7H2,1-3H3;1H
SMILES	CCN=C=NCCCN(C)C.Cl