Anti-DOK1 Antibody |产品详情|进口榴莲视频免费观看采购网

您好，欢迎来到榴莲视频下载地址入口生物网站！请登录注册

我的订单 | 联系榴莲视频下载地址入口 | 在线客服QQ：3012681483 | 客服电话：400-968-7988 | 工作时间：08:30-17:30

主营产品： ELISA8008APP幸福宝榴莲、抗体、补体血清、兔补体、干扰素、小鼠测温仪、进口榴莲视频免费观看、Quidel代理、Swant代理、PBL Assay Science代理

所在位置：首页 > 产品中心 > Antibodies > Antibodies产品

订购信息

上海榴莲视频下载地址入口生物科技公司

Tel:400-968-7988 021-33779008

Anti-DOK1 Antibody

品牌：Antibodies

货号：

规格：50µl

货期：

立即购买加入购物车

Anti-DOK1 Antibody

商品详情参考文献相关资料

Name:	Anti-DOK1 Antibody See all DOK1 primary antibodies
Description:	Rabbit polyclonal antibody to DOK1.
Applications:	WB, IHC
Dilutions:	WB: 1:500 - 1:2000, IHC: 1:50 - 1:200.
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant protein of human DOK1.
Protein Length:	481
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Function:	DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same on ITGB3.
Tissue Specificity:	Expressed in pancreas, heart, leukocyte and spleen. Expressed in both resting and activated peripheral blood T-cells. Expressed in breast cancer.
Sequence Similarities:	Belongs to the DOK family. Type A subfamily.
Post-Translational Modification:	Constitutively tyrosine-phosphorylated. Phosphorylated by TEC (By similarity). Phosphorylated by LYN (By similarity). Phosphorylated on tyrosine residues by the insulin receptor kinase. Results in the negative regulation of the insulin signaling pathway. Phosphorylated on tyrosine residues by SRMS.
Cellular locations:	Cytoplasm. Nucleus.
Database Links:	Entrez Gene: 1796?Human Entrez Gene: 13448?Mouse Entrez Gene: 312477?Rat Omim: 602919?Human SwissProt: Q99704?Human SwissProt: P97465?Mouse SwissProt: Q4QQV2?Rat Unigene: 103854?Human Unigene: 156?Mouse Unigene: 117974?Rat
Synonyms:	Docking protein 1 Antibody Docking protein 1 62kD Antibody DOK 1 Antibody DOK1 Antibody DOK1_HUMAN Antibody Downstream of tyrosine kinase 1 Antibody p62(dok) Antibody P62DOK Antibody pp62 Antibody
Information:	Target information shown above is from the UniProt Consortium.