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Anti-CYP3A4 Antibody |产品详情|进口榴莲视频免费观看采购网





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    Anti-CYP3A4 Antibody
    品牌:Antibodies
    货号:
    规格:100µl
    货期:

    Anti-CYP3A4 Antibody

    商品详情 参考文献 相关资料
    Name: Anti-CYP3A4 Antibody
    See all CYP3A4 primary antibodies
    Description: Rabbit polyclonal antibody to CYP3A4.
    Applications: WB, IHC, FC
    Dilutions: WB: 1:500 - 1:1000, IHC: 1:20 - 1:50, FC: 1:20 - 1:50.
    Reactivity: Human, Mouse, Rat
    Immunogen: A synthetic peptide of human CYP3A4.
    Protein Length: 503
    Host: Rabbit
    Clonality: Polyclonal
    Isotype: IgG
    Conjugate: Unconjugated
    Purification: Affinity purification.
    Product Form: Liquid
    Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
    Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
    Function: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2-exo-monooxygenase. The enzyme also hydroxylates etoposide (PubMed:11159812). Catalyzes 4-beta-hydroxylation of cholesterol. May catalyze 25-hydroxylation of cholesterol in vitro (PubMed:21576599).
    Tissue Specificity: Expressed in prostate and liver. According to some authors, it is not expressed in brain (PubMed:19094056). According to others, weak levels of expression are measured in some brain locationss (PubMed:19359404 and PubMed:18545703). Also expressed in epithelium of the small intestine and large intestine, bile duct, nasal mucosa, kidney, adrenal cortex, epithelium of the gastric mucosa with intestinal metaplasia, gallbladder, intercalated ducts of the pancreas, chief cells of the parathyroid and the corpus luteum of the ovary (at protein level).
    Sequence Similarities: Belongs to the cytochrome P450 family.
    Post-Translational Modification: Polyubiquitinated in the presence of AMFR and UBE2G1 and also STUB1/CHIP and UBE2D1 (in vitro).
    Cellular locations: Endoplasmic reticulum membrane. Microsome membrane.
    Database Links:
  1. Entrez Gene: 1576?Human
  2. Omim: 124010?Human
  3. SwissProt: P08684?Human
  4. Unigene: 728751?Human
  5. Synonyms:
  6. 1,8-cineole 2-exo-monooxygenase Antibody
  7. Albendazole monooxygenase Antibody
  8. Albendazole sulfoxidase Antibody
  9. CP33 Antibody
  10. CP34 Antibody
  11. CP3A4_HUMAN Antibody
  12. CYP3 Antibody
  13. CYP3A Antibody
  14. CYP3A3 Antibody
  15. CYP3A4 Antibody
  16. CYPIIIA3 Antibody
  17. CYPIIIA4 Antibody
  18. Cytochrome P450 3A3 Antibody
  19. Cytochrome P450 3A4 Antibody
  20. Cytochrome P450 family 3 subfamily A polypeptide 4 Antibody
  21. Cytochrome P450 HLp Antibody
  22. Cytochrome P450 NF-25 Antibody
  23. Cytochrome P450 subfamily IIIA polypeptide 4 Antibody
  24. cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3 Antibody
  25. cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 Antibody
  26. Cytochrome P450-PCN1 Antibody
  27. Glucocorticoid inducible P450 Antibody
  28. HLP Antibody
  29. MGC126680 Antibody
  30. NF 25 Antibody
  31. NF25 Antibody
  32. Nifedipine oxidase Antibody
  33. P450 III steroid inducible Antibody
  34. P450 PCN1 Antibody
  35. P450, family III Antibody
  36. P450C3 Antibody
  37. P450PCN1 Antibody
  38. Quinine 3 monooxygenase Antibody
  39. Quinine 3-monooxygenase Antibody
  40. Taurochenodeoxycholate 6 alpha hydroxylase Antibody
  41. Taurochenodeoxycholate 6-alpha-hydroxylase Antibody
  42. Information: Target information shown above is from the UniProt Consortium.
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