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Anti-Cyclin L1 (E491) Antibody |产品详情|进口榴莲视频免费观看采购网


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    Anti-Cyclin L1 (E491) Antibody
    品牌：Antibodies
    货号：
    规格：50µl
    货期：

    Anti-Cyclin L1 (E491) Antibody
    商品详情 参考文献 相关资料
    Name: Anti-Cyclin L1 (E491) Antibody
    See all Cyclin L1 primary antibodies
    Description: Rabbit polyclonal antibody to Cyclin L1 (E491)
    Specificity: Cyclin-L1 (E491) pAb detects endogenous levels of Cyclin-L1 protein.
    Applications: WB, IHC
    Reactivity: Human, Mouse, Rat
    Immunogen: Synthetic peptide, corresponding to amino acids 460-518 of Human Cyclin L1.
    Host: Rabbit
    Clonality: Polyclonal
    Conjugate: Unconjugated
    Molecular Weight: ~ 60 kDa
    Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
    Product Form: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
    Function: Involved in pre-mRNA splicing. Functions in association with cyclin-dependent kinases (CDKs) (PubMed:18216018). Inhibited by the CDK-specific inhibitor CDKN1A/p21 (PubMed:11980906). May play a role in the regulation of RNA polymerase II (pol II). May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC) (PubMed:12414649, PubMed:15700036).
    Tissue Specificity: Widely expressed. Overexpression in primary tumors of head and neck squamous cell carcinomas (HNSCC).
    Sequence Similarities: Belongs to the cyclin family. Cyclin L subfamily.
    Cellular locations: Nucleus speckle. Nucleus > Nucleoplasm.

    Found in nuclear intrachromatin granules clusters (IGC), also called nuclear speckles, which are storage compartments for nuclear proteins involved in mRNA processing.
    Database Links:
  2. Entrez Gene: 57018?Human
  3. Entrez Gene: 56706?Mouse
  4. Entrez Gene: 114121?Rat
  5. Omim: 613384?Human
  6. SwissProt: Q9UK58?Human
  7. SwissProt: Q52KE7?Mouse
  8. SwissProt: Q9R1Q2?Rat
  9. Unigene: 4859?Human
  10. Unigene: 175612?Mouse
  11. Unigene: 12962?Rat
    		12.
    Synonyms:
  12. Ania 6a Antibody
  13. CCNL1 Antibody
  14. CCNL1_HUMAN Antibody
  15. Cyclin L Antibody
  16. Cyclin L gamma Antibody
  17. Cyclin L1 Antibody
  18. Cyclin-L Antibody
  19. Cyclin-L1 Antibody
    		20.
    Information: Target information shown above is from the UniProt Consortium.
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