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Anti-COPS2 Antibody |产品详情|进口榴莲视频免费观看采购网


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    Anti-COPS2 Antibody
    品牌：Antibodies
    货号：
    规格：50µl
    货期：

    Anti-COPS2 Antibody
    商品详情 参考文献 相关资料
    Name: Anti-COPS2 Antibody
    See all COPS2 primary antibodies
    Description: Rabbit polyclonal antibody to COPS2
    Specificity: The antibody detects endogenous levels of total COPS2 protein.
    Applications: WB, IF
    Reactivity: Human, Mouse, Rat
    Immunogen: Synthesized peptide derived from internal of human COPS2.
    Host: Rabbit
    Clonality: Polyclonal
    Conjugate: Unconjugated
    Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Concentration: 1.0mg / ml
    Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
    Storage: Store at -20˚C
    Function: Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1.
    Sequence Similarities: Belongs to the CSN2 family.
    Post-Translational Modification: Phosphorylated by CK2 and PKD kinases.
    Cellular locations: Cytoplasm. Nucleus.
    Database Links:
  2. Entrez Gene: 9318 Human
  3. Entrez Gene: 12848 Mouse
  4. Entrez Gene: 261736 Rat
  5. Omim: 604508 Human
  6. SwissProt: P61201 Human
  7. SwissProt: P61202 Mouse
  8. SwissProt: P61203 Rat
  9. Unigene: 369614 Human
  10. Unigene: 3596 Mouse
  11. Unigene: 11556 Rat
    		12.
    Synonyms:
  12. ALIEN Antibody
  13. Alien Drosophila himolog of Antibody
  14. Alien homolog Antibody
  15. COP 9 Antibody
  16. COP9 Antibody
  17. COP9 constitutive photomorphogenic homolog subunit 2 Antibody
  18. COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) Antibody
  19. COP9 signalosome complex subunit 2 Antibody
  20. COPS 2 Antibody
  21. Cops2 Antibody
  22. CSN2 Antibody
  23. CSN2_HUMAN Antibody
  24. JAB1 containing signalosome subunit 2 Antibody
  25. JAB1-containing signalosome subunit 2 Antibody
  26. SGN 2 Antibody
  27. SGN2 Antibody
  28. Signalosome subunit 2 Antibody
  29. Thyroid Hormone Receptor Interactor 15 Antibody
  30. Thyroid Hormone Receptor Interactor15 Antibody
  31. Thyroid receptor-interacting protein 15 Antibody
  32. TR-interacting protein 15 Antibody
  33. TRIP 15 Antibody
  34. TRIP-15 Antibody
  35. TRIP15 Antibody
    		36.
    Information: Target information shown above is from the UniProt Consortium.
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