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Anti-Clathrin Heavy Chain Antibody |产品详情|进口榴莲视频免费观看采购网





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    Anti-Clathrin Heavy Chain Antibody
    品牌:Antibodies
    货号:
    规格:100µg
    货期:

    Anti-Clathrin Heavy Chain Antibody

    商品详情 参考文献 相关资料
    Name: Anti-Clathrin Heavy Chain Antibody
    See all Clathrin Heavy Chain primary antibodies
    Description: Mouse monoclonal (BF-06) antibody to Clathrin Heavy Chain.
    Specificity: The antibody BF-06 recognizes clathrin heavy chain, an ubiquitously expressed 180 kDa protein involved in receptor-mediated endocytosis.
    Applications: FC, IP, WB, ICC, ELISA
    Reactivity: Human, Porcine, Mouse, Rat, Bovine
    Host: Mouse
    Clonality: Monoclonal
    Clone: BF-06
    Isotype: IgM
    Conjugate: Unconjugated
    Purification: Purified from ascites by precipitation methods and ion exchange chromatography.
    Concentration: 1 mg/ml
    Purity: > 95% (by SDS-PAGE)
    Product Form: Liquid
    Formulation: Supplied in Tris Buffered Saline, pH 8.0, with 15mM Sodium Azide.
    Storage: Store at 2-8°C.
    Function: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network (By similarity). Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge (PubMed:15858577,PubMed:16968737). The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (By similarity). Plays a role in early autophagosome formation (By similarity).
    Sequence Similarities: Belongs to the clathrin heavy chain family.
    Cellular locations: Cytoplasmic vesicle membrane. Membrane > Coated pit. Melanosome. Cytoplasm > Cytoskeleton > Spindle.

    Cytoplasmic face of coated pits and vesicles. In complex with TACC3 and CKAP5 (forming the TACC3/ch-TOG/clathrin complex) localized to inter-microtubule bridges in mitotic spindles.
    Database Links:
  1. Entrez Gene: 281080 Cow
  2. Entrez Gene: 1213 Human
  3. Entrez Gene: 67300 Mouse
  4. Entrez Gene: 54241 Rat
  5. Omim: 118955 Human
  6. SwissProt: P49951 Cow
  7. SwissProt: P53675 Human
  8. SwissProt: Q00610 Human
  9. SwissProt: Q68FD5 Mouse
  10. SwissProt: P11442 Rat
  11. Unigene: 491351 Human
  12. Unigene: 479526 Mouse
  13. Unigene: 3589 Rat
  14. Synonyms:
  15. CHC17 Antibody
  16. Clathrin heavy chain Antibody
  17. Clathrin heavy chain 1 Antibody
  18. Clathrin heavy chain 2 Antibody
  19. Clathrin heavy chain like 1 Antibody
  20. Clathrin heavy chain on chromosome 17 Antibody
  21. Clathrin heavy polypeptide Antibody
  22. CLH 17 Antibody
  23. CLH 22 Antibody
  24. CLH-17 Antibody
  25. CLH17 Antibody
  26. CLH1_HUMAN Antibody
  27. CLH22 Antibody
  28. CLTC Antibody
  29. CLTCL Antibody
  30. CLTCL1 Antibody
  31. CLTCL2 Antibody
  32. CLTD Antibody
  33. Hc Antibody
  34. KIAA0034 Antibody
  35. Information: Target information shown above is from the UniProt Consortium.
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