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Anti-CENPU Antibody |产品详情|进口榴莲视频免费观看采购网


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    Anti-CENPU Antibody
    品牌：Antibodies
    货号：
    规格：100µl
    货期：

    Anti-CENPU Antibody
    商品详情 参考文献 相关资料
    Name: Anti-CENPU Antibody
    See all CENPU primary antibodies
    Description: Rabbit polyclonal antibody to CENPU
    Specificity: The antibody detects endogenous levels of total CENPU protein.
    Applications: IHC
    Reactivity: Human
    Immunogen: Full length fusion protein
    Host: Rabbit
    Clonality: Polyclonal
    Conjugate: Unconjugated
    Purification: Antigen affinity purification.
    Concentration: 1.6mg / ml
    Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
    Storage: Store at -20?C
    Function: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Plays an important role in the correct PLK1 localization to the mitotic kinetochores. A scaffold protein responsible for the initial recruitment and maintenance of the kinetochore PLK1 population until its degradation. Involved in transcriptional repression.
    Tissue Specificity: Expressed at high levels in the testis, fetal liver, thymus, bone marrow and at lower levels in the lymph nodes, placenta, colon and spleen. Present in all cell lines examined, including B-cells, T-cells, epithelial cells and fibroblast cells. Expressed at high levels in glioblastoma cell lines.
    Post-Translational Modification: Phosphorylated by PLK1 at Thr-78, creating a self-tethering site that specifically interacts with the polo-box domain of PLK1.
    Cellular locations: Cytoplasm. Nucleus. Chromosome > Centromere > Kinetochore.

    Localizes in the kinetochore domain of centromeres. Colocalizes with PLK1 at the interzone between the inner and the outer kinetochore plates.
    Database Links:
  2. Entrez Gene: 79682?Human
  3. Omim: 611511?Human
  4. SwissProt: Q71F23?Human
  5. Unigene: 575032?Human
    		6.
    Synonyms:
  6. CENP U Antibody
  7. CENP-50 Antibody
  8. CENP-U Antibody
  9. CENP50 Antibody
  10. CENPU Antibody
  11. CENPU50 Antibody
  12. CENPU_HUMAN Antibody
  13. centromere protein of 50 kDa Antibody
  14. Centromere protein U Antibody
  15. FLJ23468 Antibody
  16. HHV8 LNAIP1 Antibody
  17. ICEN24 Antibody
  18. Interphase centromere complex protein 24 Antibody
  19. Kaposi Sarcoma Herpesvirus latent nuclear antigen interacting protein 1 Antibody
  20. KLIP-1 Antibody
  21. KLIP1 Antibody
  22. KSHV latent nuclear antigen interacting protein 1 Antibody
  23. KSHV latent nuclear antigen-interacting protein 1 Antibody
  24. KSHV LNAIP1 Antibody
  25. LNAIP 1 Antibody
  26. LNAIP-1 Antibody
  27. MLF1 Interacting Protein/PBIP1 Antibody
  28. MLF1-interacting protein Antibody
  29. MLF1IP Antibody
  30. MLF1IP1 Antibody
  31. PBIP1 Antibody
  32. Polo-box-interacting protein 1 Antibody
    		33.
    Information: Target information shown above is from the UniProt Consortium.
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