Anti-CDK8 Antibody |产品详情|进口榴莲视频免费观看采购网

您好，欢迎来到榴莲视频下载地址入口生物网站！请登录注册

我的订单 | 联系榴莲视频下载地址入口 | 在线客服QQ：3012681483 | 客服电话：400-968-7988 | 工作时间：08:30-17:30

主营产品： ELISA8008APP幸福宝榴莲、抗体、补体血清、兔补体、干扰素、小鼠测温仪、进口榴莲视频免费观看、Quidel代理、Swant代理、PBL Assay Science代理

网站首页产品中心代理品牌新闻资讯资源中心关于榴莲视频下载地址入口

所在位置：首页 > 产品中心 > Antibodies > Antibodies产品

订购信息

上海榴莲视频下载地址入口生物科技公司

Tel:400-968-7988 021-33779008

Anti-CDK8 Antibody

品牌：Antibodies

货号：

规格：100µl

货期：

应用：

咨询客服

立即购买加入购物车

Anti-CDK8 Antibody

商品详情参考文献相关资料

Overview

Name:	Anti-CDK8 Antibody See all CDK8 primary antibodies
Description:	Rabbit polyclonal antibody to CDK8
Specificity:	The antibody detects endogenous level of total CDK8 polyclonal antibody.
Applications:	IHC
Reactivity:	Human
Immunogen:	Recombinant human Cyclin-dependent kinase 8 protein(365-464aa)
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen Affinity purified
Concentration:	1.0mg / mL
Formulation:	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:	Store at -20?C

Target

Function:	Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex. Phosphorylates CCNH leading to down-regulation of the TFIIH complex and transcriptional repression. Recruited through interaction with MAML1 to hyperphosphorylate the intracellular domain of NOTCH, leading to its degradation.
Sequence Similarities:	Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Cellular locations:	Nucleus.
Database Links:	Entrez Gene: 1024?Human Omim: 603184?Human SwissProt: P49336?Human Unigene: 382306?Human
Synonyms:	Cdk8 Antibody CDK8 protein kinase Antibody CDK8_HUMAN Antibody Cell Division Kinase 8 Antibody Cell division protein kinase 8 Antibody Cyclin Dependent kinase 8 Antibody Cyclin-dependent kinase 8 Antibody K35 Antibody Mediator complex subunit cdk8 Antibody Mediator of RNA polymerase II transcription subunit cdk8 Antibody Protein kinase K35 Antibody
Information:	Target information shown above is from the UniProt Consortium.