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 Anti-Cdc6 (phospho-S54) Antibody |产品详情|进口榴莲视频免费观看采购网





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    Anti-Cdc6 (phospho-S54) Antibody
    品牌:Antibodies
    货号:
    规格:50µl
    货期:

    Anti-Cdc6 (phospho-S54) Antibody

    商品详情 参考文献 相关资料
    Name: Anti-Cdc6 (phospho-S54) Antibody
    See all Cdc6 primary antibodies
    Description: Rabbit polyclonal antibody to Cdc6 (phospho-S54)
    Specificity: p-Cdc6 (S54) pAb detects endogenous levels of Cdc6 only when phosphorylated at Ser54.
    Applications: WB, IHC
    Reactivity: Human, Mouse, Rat
    Immunogen: Synthetic phosphopeptide derived from human Cdc6 around the phosphorylation site of Serine 54.
    Host: Rabbit
    Clonality: Polyclonal
    Conjugate: Unconjugated
    Molecular Weight: ~ 62 kDa
    Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
    Product Form: 1mg/ml in PBS?with?0.1%?Sodium?Azide,?50%?Glycerol.
    Function: Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
    Involvement in Disease: Meier-Gorlin syndrome 5: A syndrome characterized by bilateral microtia, aplasia/hypoplasia of the patellae, and severe intrauterine and postnatal growth retardation with short stature and poor weight gain. Additional clinical findings include anomalies of cranial sutures, microcephaly, apparently low-set and simple ears, microstomia, full lips, highly arched or cleft palate, micrognathia, genitourinary tract anomalies, and various skeletal anomalies. While almost all cases have primordial dwarfism with substantial prenatal and postnatal growth retardation, not all cases have microcephaly, and microtia and absent/hypoplastic patella are absent in some. Despite the presence of microcephaly, intellect is usually normal.
    Sequence Similarities: Belongs to the CDC6/cdc18 family.
    Cellular locations: Nucleus. Cytoplasm.

    The protein is nuclear in G1 and cytoplasmic in S-phase cells (PubMed:9566895).
    Database Links:
  1. Entrez Gene: 990?Human
  2. Entrez Gene: 23834?Mouse
  3. Entrez Gene: 360621?Rat
  4. Omim: 602627?Human
  5. SwissProt: Q99741?Human
  6. SwissProt: O89033?Mouse
  7. Unigene: 405958?Human
  8. Unigene: 20912?Mouse
  9. Unigene: 219688?Rat
  10. Synonyms:
  11. Cdc 18L Antibody
  12. Cdc 6 Antibody
  13. CDC18 (cell division cycle 18, S.pombe, homolog) like Antibody
  14. CDC18 (S.pombe) Antibody
  15. Cdc18 related protein Antibody
  16. CDC18(S.pombe) Antibody
  17. Cdc18-related protein Antibody
  18. Cdc18L Antibody
  19. Cdc6 Antibody
  20. CDC6 cell division cycle 6 homolog Antibody
  21. CDC6 related protein Antibody
  22. CDC6-related protein Antibody
  23. Cdc6p Antibody
  24. CDC6_HUMAN Antibody
  25. CELL CYCLE CONTROLLER CDC6 Antibody
  26. Cell division control protein 6 Antibody
  27. Cell division control protein 6 homolog Antibody
  28. Cell division cycle 6 homolog Antibody
  29. Cell division cycle 6 homolog (S. cerevisiae) Antibody
  30. Cell division cycle 6, S. cerevisiae, homolog of Antibody
  31. HsCDC 6 Antibody
  32. HsCDC18 Antibody
  33. HsCDC6 Antibody
  34. p62 Antibody
  35. p62(cdc 6) Antibody
  36. p62(cdc6) Antibody
  37. Information: Target information shown above is from the UniProt Consortium.
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