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Anti-CDC25B Antibody |产品详情|进口榴莲视频免费观看采购网


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    Anti-CDC25B Antibody
    品牌：Antibodies
    货号：
    规格：100µl
    货期：

    Anti-CDC25B Antibody
    商品详情 参考文献 相关资料
    Name: Anti-CDC25B Antibody
    See all CDC25B primary antibodies
    Description: Rabbit polyclonal antibody to CDC25B
    Specificity: The antibody detects endogenous levels of total CDC25B protein.
    Applications: WB, IHC
    Dilutions: Western blotting: 1:200-1:1000 Immunohistochemistry: 1:50-1:200
    Reactivity: Human, Mouse
    Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human cell division cycle 25B
    Host: Rabbit
    Clonality: Polyclonal
    Conjugate: Unconjugated
    Purification: Antigen affinity purification.
    Concentration: 2mg / ml
    Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
    Storage: Store at -20?C
    Function: Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.
    Sequence Similarities: Belongs to the MPI phosphatase family.
    Post-Translational Modification: Phosphorylated by BRSK1 in vitro. Phosphorylated by CHEK1, which inhibits the activity of this protein. Phosphorylation at Ser-353 by AURKA might locally participate in the control of the onset of mitosis. Phosphorylation by MELK at Ser-169 promotes localization to the centrosome and the spindle poles during mitosis. Phosphorylation at Ser-323 and Ser-375 by MAPK14 is required for binding to 14-3-3 proteins.
    Cellular locations: Cytoplasm > Cytoskeleton > Microtubule organizing center > Centrosome. Cytoplasm > Cytoskeleton > Spindle pole.
    Database Links:
  2. Entrez Gene: 994?Human
  3. Entrez Gene: 12531?Mouse
  4. Omim: 116949?Human
  5. SwissProt: P30305?Human
  6. SwissProt: P30306?Mouse
  7. Unigene: 153752?Human
  8. Unigene: 38444?Mouse
    		9.
    Synonyms:
  9. AI604853 Antibody
  10. Cdc 25B Antibody
  11. Cdc25B Antibody
  12. CDC25HU2 Antibody
  13. Cdc25m2 Antibody
  14. Cell division cycle 25 homolog B Antibody
  15. Cell division cycle 25B Antibody
  16. Cell division cycle 25B isoform 1 Antibody
  17. Cell division cycle 25B isoform 2 Antibody
  18. Cell division cycle 25B isoform 3 Antibody
  19. Cell division cycle 25B isoform 4 Antibody
  20. Cell division cycle 25B isoform 5 Antibody
  21. Dual specificity phosphatase Cdc25B Antibody
  22. EC 3.1.3.48 Antibody
  23. M phase inducer phosphatase 2 Antibody
  24. M-phase inducer phosphatase 2 Antibody
  25. MPIP2_HUMAN Antibody
    		26.
    Information: Target information shown above is from the UniProt Consortium.
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