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Anti-BID Antibody

品牌：Antibodies

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规格：50µl

货期：

应用：

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Anti-BID Antibody

商品详情参考文献相关资料

Overview

Name:	Anti-BID Antibody See all BID primary antibodies
Description:	Rabbit polyclonal antibody to BID
Specificity:	BID pAb detects endogenous levels of Bid protein.
Applications:	WB, IHC
Reactivity:	Human, Mouse, Rat
Immunogen:	Recombinant full length Human BID.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 22 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1mg/ml in PBS?with?0.1%?Sodium?Azide,?50%?Glycerol.

Target

Function:	The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.
Tissue Specificity:	Isoform 2 and isoform 3 are expressed in spleen, bone marrow, cerebral and cerebellar cortex. Isoform 2 is expressed in spleen, pancreas and placenta (at protein level). Isoform 3 is expressed in lung, pancreas and spleen (at protein level). Isoform 4 is expressed in lung and pancreas (at protein level).
Post-Translational Modification:	TNF-alpha induces a caspase-mediated cleavage of p22 BID into a major p15 and minor p13 and p11 products.
Cellular locations:	Cytoplasm. Mitochondrion membrane. When uncleaved, it is predominantly cytoplasmic.
Database Links:	Entrez Gene: 637?Human Entrez Gene: 12122?Mouse Entrez Gene: 64625?Rat Omim: 601997?Human SwissProt: P55957?Human SwissProt: P70444?Mouse SwissProt: Q9JLT6?Rat Unigene: 591054?Human Unigene: 235081?Mouse Unigene: 31142?Rat
Synonyms:	Apoptic death agonist Antibody Apoptotic death agonist BID Antibody BH3 interacting domain death agonist Antibody BH3 interacting domain death agonist p11 Antibody BH3 interacting domain death agonist p13 Antibody BH3 interacting domain death agonist p15 Antibody BH3-interacting domain death agonist p11 Antibody Bid Antibody BID isoform ES(1b) Antibody BID isoform L(2) Antibody BID isoform Si6 Antibody BID_HUMAN Antibody Desmocollin type 4 Antibody FP497 Antibody Human BID coding sequence Antibody MGC15319 Antibody MGC42355 Antibody p11 BID Antibody p13 BID Antibody p15 BID Antibody p22 BID Antibody
Information:	Target information shown above is from the UniProt Consortium.