Anti-ATF1 Antibody |产品详情|进口榴莲视频免费观看采购网

您好，欢迎来到榴莲视频下载地址入口生物网站！请登录注册

我的订单 | 联系榴莲视频下载地址入口 | 在线客服QQ：3012681483 | 客服电话：400-968-7988 | 工作时间：08:30-17:30

主营产品： ELISA8008APP幸福宝榴莲、抗体、补体血清、兔补体、干扰素、小鼠测温仪、进口榴莲视频免费观看、Quidel代理、Swant代理、PBL Assay Science代理

网站首页产品中心代理品牌新闻资讯资源中心关于榴莲视频下载地址入口

所在位置：首页 > 产品中心 > Antibodies > Antibodies产品

订购信息

上海榴莲视频下载地址入口生物科技公司

Tel:400-968-7988 021-33779008

Anti-ATF1 Antibody

品牌：Antibodies

货号：

规格：50µl

货期：

应用：

咨询客服

立即购买加入购物车

Anti-ATF1 Antibody

商品详情参考文献相关资料

Overview

Name:	Anti-ATF1 Antibody See all ATF1 primary antibodies
Description:	Rabbit polyclonal antibody to ATF1
Specificity:	The antibody detects endogenous levels of total ATF1 protein.
Applications:	WB, IF
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthesized peptide derived from internal of human ATF1.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1.0mg / ml
Formulation:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20˚C

Target

Function:	This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.
Involvement in Disease:	Angiomatoid fibrous histiocytoma: A distinct variant of malignant fibrous histiocytoma that typically occurs in children and adolescents and is manifest by nodular subcutaneous growth. Characteristic microscopic features include lobulated sheets of histiocyte-like cells intimately associated with areas of hemorrhage and cystic pseudovascular spaces, as well as a striking cuffing of inflammatory cells, mimicking a lymph node metastasis.
Sequence Similarities:	Belongs to the bZIP family. ATF subfamily.
Post-Translational Modification:	Phosphorylated at Ser-198 by HIPK2 in response to genotoxic stress. This phosphorylation promotes transcription repression of FTH1 and other antioxidant detoxification genes. The CDK3-mediated phosphorylation at Ser-63 promotes its transactivation and transcriptional activities. Phosphorylated at Ser-63 by RPS6KA4 and RPS6KA5 in response to mitogenic or stress stimuli.
Cellular locations:	Nucleus.
Database Links:	Entrez Gene: 466 Human Entrez Gene: 11908 Mouse Entrez Gene: 315305 Rat Omim: 123803 Human SwissProt: P18846 Human SwissProt: P81269 Mouse Unigene: 648565 Human Unigene: 473546 Mouse Unigene: 676 Mouse Unigene: 105304 Rat
Synonyms:	Activating transcription factor 1 Antibody ATF 1 Antibody ATF1 Antibody ATF1 EWS fusion gene Antibody ATF1 FUS fusion gene Antibody ATF1_HUMAN Antibody cAMP dependent transcription factor 1 Antibody cAMP-dependent transcription factor ATF-1 Antibody Cyclic AMP dependent transcription factor ATF 1 Antibody Cyclic AMP dependent transcription factor ATF1 Antibody Cyclic AMP-dependent transcription factor ATF-1 Antibody EWS AFT1 Antibody FUS ATF 1 Antibody FUS/ATF 1 Antibody Protein TREB36 Antibody RNA binding protein activating transcription factor 1 fusion protein Antibody TREB 36 Antibody TREB36 Antibody TREB36 protein Antibody
Information:	Target information shown above is from the UniProt Consortium.