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Anti-SLC24A6 Antibody

品牌：Antibodies

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规格：100µl

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Anti-SLC24A6 Antibody

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Name:	Anti-SLC24A6 Antibody See all SLC24A6 primary antibodies
Description:	Rabbit polyclonal antibody to SLC24A6
Specificity:	The antibody detects endogenous levels of total SLC24A6 protein.
Applications:	WB, IHC
Reactivity:	Human
Immunogen:	Synthetic peptide corresponding to a region derived from internal residues of human solute carrier family 8 (sodium / lithium / calcium exchanger), member B1
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antigen affinity purification.
Concentration:	1mg / ml
Formulation:	Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Storage:	Store at -20?C

Function:	Mitochondrial sodium/calcium antiporter that mediates sodium-dependent calcium efflux from mitochondrion, thereby acting as a key regulator of mitochondrion calcium homeostasis. Regulates rates of glucose-dependent insulin secretion in pancreatic beta-cells during the first phase of insulin secretion: acts by mediating efflux of calcium from mitochondrion, thereby affecting cytoplasmic calcium responses. Able to transport Ca(2+) in exchange of either Li(+) or Na(+), explaining how Li(+) catalyzes Ca(2+) exchange. In contrast to other members of the family its function is independent of K(+).
Tissue Specificity:	Present in pancreatic beta-cells (at protein level).
Sequence Similarities:	Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
Cellular locations:	Mitochondrion inner membrane.
Database Links:	Entrez Gene: 80024?Human Omim: 609841?Human SwissProt: Q6J4K2?Human Unigene: 286194?Human
Synonyms:	FLJ22233 Antibody Na(+)/K(+)/Ca(2+) exchange protein 6 Antibody Na(+)/K(+)/Ca(2+)-exchange protein 6 Antibody NCKX6 Antibody NCKX6_HUMAN Antibody NCLX Antibody SLC24A6 Antibody Sodium/potassium/calcium exchanger Antibody Sodium/potassium/calcium exchanger 6 Antibody Solute carrier family 24 (sodium/potassium/calcium exchanger) member 6 Antibody Solute carrier family 24 member 6 Antibody
Information:	Target information shown above is from the UniProt Consortium.