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Anti-Hexokinase I Antibody

品牌：Antibodies

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规格：100µl

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Anti-Hexokinase I Antibody

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Overview

Name:	Anti-Hexokinase I Antibody See all Hexokinase I primary antibodies
Description:	Rabbit polyclonal antibody to Hexokinase I.
Applications:	WB, IHC
Dilutions:	WB: 1:500 - 1:1000, IHC: 1:50 - 1:100.
Reactivity:	Human
Immunogen:	A synthetic peptide of human HK1.
Protein Length:	917
Host:	Rabbit
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Affinity purification.
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Tissue Specificity:	Isoform 2 is erythrocyte specific. Isoform 3 and isoform 4 are testis-specific.
Involvement in Disease:	Hexokinase deficiency: Rare autosomal recessive disease with nonspherocytic hemolytic anemia as the predominant clinical feature. Neuropathy, hereditary motor and sensory, Russe type: An autosomal recessive progressive complex peripheral neuropathy characterized by onset in the first decade of distal lower limb weakness and muscle atrophy resulting in walking difficulties. Distal impairment of the upper limbs usually occurs later, as does proximal lower limb weakness. There is distal sensory impairment, with pes cavus and areflexia. Laboratory studies suggest that it is a myelinopathy resulting in reduced nerve conduction velocities in the demyelinating range as well as a length-dependent axonopathy.
Sequence Similarities:	Belongs to the hexokinase family.
Cellular locations:	Mitochondrion outer membrane. Its hydrophobic N-terminal sequence may be involved in membrane binding.
Database Links:	Entrez Gene: 3098?Human Omim: 142600?Human SwissProt: P19367?Human Unigene: 370365?Human
Synonyms:	BB404130 Antibody Brain form hexokinase Antibody dea Antibody DrHXK1 Antibody EC 2.7.1.1 Antibody Glycolytic enzyme Antibody HEXOKIN Antibody Hexokinase 1 Antibody hexokinase I Antibody Hexokinase PI Antibody Hexokinase type I Antibody Hexokinase, tumor isozyme Antibody Hexokinase-1 Antibody Hexokinase-A Antibody HK I Antibody HK1 Antibody HK1 tb Antibody Hk1-s Antibody HK1-ta Antibody HK1-tb Antibody HK1-tc Antibody HKD Antibody HKI Antibody HMSNR Antibody HXK1 Antibody HXK1_HUMAN Antibody im:7148527 Antibody mHk1-s Antibody wu:fc09d08 Antibody wu:fc16e02 Antibody wu:fc21e02 Antibody wu:fq14b11 Antibody zgc:55790 Antibody zgc:77618 Antibody
Information:	Target information shown above is from the UniProt Consortium.