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 Anti-SEPT4 Antibody |产品详情|进口榴莲视频免费观看采购网





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    Anti-SEPT4 Antibody
    品牌:Antibodies
    货号:
    规格:100µl
    货期:

    Anti-SEPT4 Antibody

    商品详情 参考文献 相关资料
    Name: Anti-SEPT4 Antibody
    See all SEPT4 primary antibodies
    Description: Rabbit polyclonal antibody to SEPT4
    Specificity: The antibody detects endogenous levels of total SEPT4 Antibody.
    Applications: IHC
    Dilutions: Immunohistochemistry: 1:50-1:200
    Reactivity: Human
    Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human septin 4
    Host: Rabbit
    Clonality: Polyclonal
    Conjugate: Unconjugated
    Purification: Antigen affinity purification.
    Concentration: 1.7mg / ml
    Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
    Storage: Store at -20?C
    Function: Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (PubMed:25588830). May play a role in platelet secretion. Isoform ARTS, but not the other isoforms, is required for the induction of cell death mediated by TGF-beta and by other apoptotic stimuli.
    Tissue Specificity: Widely expressed in ***** and fetal tissues with highest expression in ***** brain (at protein level), heart, liver and adrenal gland and fetal heart, kidney, liver and lung. Also expressed in colorectal cancers and malignant melanomas. Expressed in platelets.
    Sequence Similarities: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
    Cellular locations: Cytoplasm. Cytoplasm > Cytoskeleton. Cell projection > Cilium > Flagellum.

    In platelets, found in areas surrounding alpha-granules. Found in the sperm annulus (PubMed:25588830).
    Database Links:
  1. Entrez Gene: 5414?Human
  2. Omim: 603696?Human
  3. SwissProt: O43236?Human
  4. Unigene: 287518?Human
  5. Synonyms:
  6. Apoptosis-related protein in the TGF-beta signaling pathway Antibody
  7. ARTS Antibody
  8. Bradeion Antibody
  9. Bradeion beta Antibody
  10. Brain protein H5 Antibody
  11. CE5B3 Antibody
  12. CE5B3 beta Antibody
  13. Cell division control-related protein 2 Antibody
  14. Cerebral protein 7 Antibody
  15. H5 Antibody
  16. hCDCREL-2 Antibody
  17. hucep-7 Antibody
  18. MART Antibody
  19. Peanut-like protein 2 Antibody
  20. PNUTL2 Antibody
  21. SEP 4 Antibody
  22. SEP4 Antibody
  23. SEPT4 Antibody
  24. SEPT4_HUMAN Antibody
  25. Septin M Antibody
  26. Septin-4 Antibody
  27. Information: Target information shown above is from the UniProt Consortium.
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