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 Anti-SENP3 Antibody |产品详情|进口榴莲视频免费观看采购网


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    Anti-SENP3 Antibody
    品牌：Antibodies
    货号：
    规格：50µl
    货期：

    Anti-SENP3 Antibody
    商品详情 参考文献 相关资料
    Name: Anti-SENP3 Antibody
    See all SENP3 primary antibodies
    Description: Rabbit polyclonal antibody to SENP3
    Specificity: The antibody detects endogenous levels of total SENP3 protein.
    Applications: WB, IHC
    Reactivity: Human, Mouse
    Immunogen: Synthesized peptide derived from Internal of human SENP3.
    Host: Rabbit
    Clonality: Polyclonal
    Conjugate: Unconjugated
    Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Concentration: 1.0mg / ml
    Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
    Storage: Store at -20?C
    Function: Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability. Deconjugates SUMO2 and SUMO3 from CDCA8. Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. Required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1. Plays a role in the regulation of sumoylation status of ZNF148. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
    Sequence Similarities: Belongs to the peptidase C48 family.
    Cellular locations: Nucleus > Nucleolus. Nucleus > Nucleoplasm. Cytoplasm.

    Redistributes between the nucleolus and the nucleoplasm in response to mild oxidative stress (PubMed:19680224). Mainly found in the nucleoplasm, with low levels detected in the cytoplasmic and chromatin fractions (By similarity).
    Database Links:
  2. Entrez Gene: 26168?Human
  3. Entrez Gene: 80886?Mouse
  4. Omim: 612844?Human
  5. SwissProt: Q9H4L4?Human
  6. SwissProt: Q9EP97?Mouse
  7. Unigene: 513926?Human
  8. Unigene: 733104?Human
  9. Unigene: 284592?Mouse
  10. Unigene: 422171?Mouse
    		11.
    Synonyms:
  11. SENP3 Antibody
  12. SENP3_HUMAN Antibody
  13. Sentrin / SUMO specific protease 3 Antibody
  14. Sentrin specific protease 3 Antibody
  15. Sentrin-specific protease 3 Antibody
  16. Sentrin/SUMO-specific protease SENP3 Antibody
  17. SMT3IP1 Antibody
  18. SSP3 Antibody
  19. SUMO 1 specific protease 3 Antibody
  20. SUMO-1-specific protease 3 Antibody
  21. SUMO1 specific protease 3 Antibody
  22. SUMO1/sentrin/SMT3 specific peptidase 3 Antibody
  23. SUSP3 Antibody
    		24.
    Information: Target information shown above is from the UniProt Consortium.
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