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 Anti-RAB5A Antibody |产品详情|进口榴莲视频免费观看采购网


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    Anti-RAB5A Antibody
    品牌：Antibodies
    货号：
    规格：50µl
    货期：

    Anti-RAB5A Antibody
    商品详情 参考文献 相关资料
    Name: Anti-RAB5A Antibody
    See all RAB5A primary antibodies
    Description: Rabbit monoclonal antibody to RAB5A
    Specificity: This antibody detects endogenous levels of RAB5A and does not cross-react with related proteins.
    Applications: WB, IHC
    Reactivity: Human, Mouse, Rat
    Immunogen: Recombinant antibody.
    Host: Rabbit
    Clonality: Monoclonal
    Conjugate: Unconjugated
    Molecular Weight: ~ 24 kDa
    Purity: Protein A affinity purified
    Product Form: Recombinant Rabbit Monoclonal Antibody. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
    Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes (PubMed:10818110, PubMed:14617813, PubMed:16410077, PubMed:15378032). Contributes to the regulation of filopodia extension (PubMed:14978216). Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan (PubMed:22660413). Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3 (By similarity).
    Sequence Similarities: Belongs to the small GTPase superfamily. Rab family.
    Cellular locations: Cell membrane. Early endosome membrane. Melanosome. Cytoplasmic vesicle. Cell projection > Ruffle. Membrane. Cytoplasm > Cytosol. Cytoplasmic vesicle > Phagosome membrane. Endosome membrane.

    Enriched in stage I melanosomes (PubMed:17081065). Alternates between membrane-bound and cytosolic forms (Probable).
    Database Links:
  2. Entrez Gene: 5868?Human
  3. Entrez Gene: 271457?Mouse
  4. Entrez Gene: 64633?Rat
  5. Omim: 179512?Human
  6. SwissProt: P20339?Human
  7. SwissProt: Q9CQD1?Mouse
  8. SwissProt: M0RC99?Rat
  9. Unigene: 475663?Human
  10. Unigene: 329123?Mouse
  11. Unigene: 44477?Rat
    		12.
    Synonyms:
  12. RAB 5 Antibody
  13. RAB 5A Antibody
  14. Rab5 Antibody
  15. RAB5A Antibody
  16. RAB5A member RAS oncogene family Antibody
  17. RAB5A_HUMAN Antibody
  18. RAS associated protein RAB5A Antibody
  19. Ras related protein Rab 5A Antibody
  20. Ras-related protein Rab-5A Antibody
    		21.
    Information: Target information shown above is from the UniProt Consortium.
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