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Anti-SPARC Antibody |产品详情|进口榴莲视频免费观看采购网





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    Anti-SPARC Antibody
    品牌:Antibodies
    货号:
    规格:50µl
    货期:

    Anti-SPARC Antibody

    商品详情 参考文献 相关资料
    Name: Anti-SPARC Antibody
    See all SPARC primary antibodies
    Description: Rabbit polyclonal antibody to SPARC.
    Applications: WB, IHC
    Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200.
    Reactivity: Human, Mouse, Rat
    Immunogen: Recombinant protein of human SPARC.
    Protein Length: 303
    Host: Rabbit
    Clonality: Polyclonal
    Isotype: IgG
    Conjugate: Unconjugated
    Purification: Affinity purification.
    Product Form: Liquid
    Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
    Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
    Function: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium s; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
    Involvement in Disease: Osteogenesis imperfecta 17: An autosomal recessive form of osteogenesis imperfecta, a connective tissue disorder characterized by low bone mass, bone fragility and susceptibility to fractures after minimal trauma. Disease severity ranges from very mild forms without fractures to intrauterine fractures and perinatal lethality. Extraskeletal manifestations, which affect a variable number of patients, are dentinogenesis imperfecta, hearing loss, and blue sclerae.
    Sequence Similarities: Belongs to the SPARC family.
    Cellular locations: Secreted > Extracellular space > Extracellular matrix > Basement membrane.

    In or around the basement membrane.
    Database Links:
  1. Entrez Gene: 6678?Human
  2. Entrez Gene: 20692?Mouse
  3. Entrez Gene: 24791?Rat
  4. Omim: 182120?Human
  5. SwissProt: P09486?Human
  6. SwissProt: P07214?Mouse
  7. SwissProt: P16975?Rat
  8. Unigene: 111779?Human
  9. Unigene: 708558?Human
  10. Unigene: 291442?Mouse
  11. Unigene: 98989?Rat
  12. Synonyms:
  13. AA517111 Antibody
  14. Basement membrane protein 40 Antibody
  15. Basement-membrane protein 40 Antibody
  16. BM 40 Antibody
  17. BM-40 Antibody
  18. BM40 Antibody
  19. Cysteine rich protein Antibody
  20. hm:zeh0062 Antibody
  21. MGC128090 Antibody
  22. OI17 Antibody
  23. ON Antibody
  24. Osteonectin Antibody
  25. Secreted acidic cystein rich glycoprotein Antibody
  26. Secreted protein acidic and cysteine rich Antibody
  27. Secreted protein acidic and rich in cysteine Antibody
  28. Secreted protein acidic cysteine rich Antibody
  29. Secreted protein acidic cysteine rich (osteonectin) Antibody
  30. SPARC Antibody
  31. SPRC Antibody
  32. SPRC_HUMAN Antibody
  33. Information: Target information shown above is from the UniProt Consortium.
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