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Anti-SNRPE Antibody |产品详情|进口榴莲视频免费观看采购网





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    Anti-SNRPE Antibody
    品牌:Antibodies
    货号:
    规格:50µl
    货期:

    Anti-SNRPE Antibody

    商品详情 参考文献 相关资料
    Name: Anti-SNRPE Antibody
    See all SNRPE primary antibodies
    Description: Rabbit polyclonal antibody to SNRPE.
    Applications: WB, IHC, IF
    Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200.
    Reactivity: Human, Mouse, Rat
    Immunogen: Recombinant protein of human SNRPE.
    Protein Length: 92
    Host: Rabbit
    Clonality: Polyclonal
    Isotype: IgG
    Conjugate: Unconjugated
    Purification: Affinity purification.
    Product Form: Liquid
    Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
    Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
    Function: Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development.
    Tissue Specificity: Widely expressed. In scalp skin, it is present in the hair follicle, the epidermis, and the dermis.
    Involvement in Disease: Hypotrichosis 11: A form of hypotrichosis, a condition characterized by the presence of less than the normal amount of hair and abnormal hair follicles and shafts, which are thin and atrophic. The extent of scalp and body hair involvement can be very variable, within as well as between families. HYPT11 is characterized by scanty or absent eyebrows and a highly variable degree of alopecia since birth, ranging from slight thinning of scalp and axillary hair to complete loss of scalp and body hair. Pubic hair remains mainly unaffected.
    Sequence Similarities: Belongs to the snRNP Sm proteins family.
    Cellular locations: Cytoplasm > Cytosol. Nucleus.

    SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
    Database Links:
  1. Entrez Gene: 6635?Human
  2. Entrez Gene: 20643?Mouse
  3. Entrez Gene: 685587?Rat
  4. Omim: 128260?Human
  5. SwissProt: P62304?Human
  6. SwissProt: P62305?Mouse
  7. Unigene: 334612?Human
  8. Unigene: 654418?Human
  9. Unigene: 249110?Mouse
  10. Synonyms:
  11. AL022645 Antibody
  12. B raf Antibody
  13. B-raf Antibody
  14. Braf Antibody
  15. C76690 Antibody
  16. HYPT11 Antibody
  17. RUXE_HUMAN Antibody
  18. Sm protein E Antibody
  19. Sm-E Antibody
  20. Small nuclear ribonucleoprotein E Antibody
  21. SmE Antibody
  22. snRNP-E Antibody
  23. snRNPE Antibody
  24. SNRPE Antibody
  25. Information: Target information shown above is from the UniProt Consortium.
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