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Anti-MAP1LC3A Antibody |产品详情|进口榴莲视频免费观看采购网


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    Anti-MAP1LC3A Antibody
    品牌：Antibodies
    货号：
    规格：50µl
    货期：

    Anti-MAP1LC3A Antibody
    商品详情 参考文献 相关资料
    Name: Anti-MAP1LC3A Antibody
    See all MAP1LC3A primary antibodies
    Description: Rabbit monoclonal antibody to MAP1LC3A
    Specificity: This antibody detects endogenous levels of MAP1LC3A and does not cross-react with related proteins.
    Applications: WB, ICC/IF, IHC, FC
    Reactivity: Human, Mouse, Rat
    Immunogen: Recombinant antibody.
    Host: Rabbit
    Clonality: Monoclonal
    Conjugate: Unconjugated
    Molecular Weight: ~ 14 kDa
    Purity: Protein A affinity purified
    Product Form: Recombinant Rabbit Monoclonal Antibody. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
    Function: Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes) (PubMed:20713600, PubMed:24290141). Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (PubMed:20713600).
    Tissue Specificity: Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.
    Sequence Similarities: Belongs to the ATG8 family.
    Post-Translational Modification: The precursor molecule is cleaved by ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II (PubMed:15187094).
    Cellular locations: Cytoplasm > Cytoskeleton. Endomembrane system. Cytoplasmic vesicle > Autophagosome membrane. Cytoplasmic vesicle > Autophagosome.

    LC3-II binds to the autophagic membranes.
    Database Links:
  2. Entrez Gene: 84557?Human
  3. Entrez Gene: 66734?Mouse
  4. Entrez Gene: 362245?Rat
  5. Omim: 601242?Human
  6. SwissProt: Q9H492?Human
  7. SwissProt: Q91VR7?Mouse
  8. SwissProt: Q6XVN8?Rat
  9. Unigene: 632273?Human
  10. Unigene: 196239?Mouse
  11. Unigene: 3135?Rat
    		12.
    Synonyms:
  12. ATG8E Antibody
  13. Autophagy-related protein LC3 A Antibody
  14. Autophagy-related ubiquitin-like modifier LC3 A Antibody
  15. LC3 Antibody
  16. LC3A Antibody
  17. MAP1 light chain 3 like protein 1 Antibody
  18. MAP1 light chain 3-like protein 1 Antibody
  19. MAP1A/1B light chain 3 A Antibody
  20. MAP1A/MAP1B LC3 A Antibody
  21. MAP1A/MAP1B light chain 3 A Antibody
  22. MAP1ALC3 Antibody
  23. MAP1BLC3 Antibody
  24. MAP1LC3A Antibody
  25. Microtubule associated proteins 1A/1B light chain 3 Antibody
  26. Microtubule-associated protein 1 light chain 3 alpha Antibody
  27. Microtubule-associated proteins 1A and 1B, light chain 3 Antibody
  28. Microtubule-associated proteins 1A/1B light chain 3A Antibody
  29. MLP3A_HUMAN Antibody
    		30.
    Information: Target information shown above is from the UniProt Consortium.
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