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 Anti-Histone H2B (K5) Antibody |产品详情|进口榴莲视频免费观看采购网


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    Anti-Histone H2B (K5) Antibody
    品牌：Antibodies
    货号：
    规格：50µl
    货期：

    Anti-Histone H2B (K5) Antibody
    商品详情 参考文献 相关资料
    Name: Anti-Histone H2B (K5) Antibody
    See all Histone H2B primary antibodies
    Description: Rabbit polyclonal antibody to Histone H2B (K5)
    Specificity: Histone H2B (K5) pAb detects endogenous levels of Histone H2B protein.
    Applications: WB, IHC, IF
    Reactivity: Human, Mouse
    Immunogen: Synthetic peptide, corresponding to amino acids N-terminus of Human Histone H2B.
    Host: Rabbit
    Clonality: Polyclonal
    Conjugate: Unconjugated
    Molecular Weight: ~ 14 kDa
    Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
    Product Form: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
    Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    Sequence Similarities: Belongs to the histone H2B family.
    Post-Translational Modification: Monoubiquitination at Lys-35 (H2BK34Ub) by the MSL1/MSL2 dimer is required for histone H3 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) methylation and transcription activation at specific gene loci, such as HOXA9 and MEIS1 loci. Similarly, monoubiquitination at Lys-121 (H2BK120Ub) by the RNF20/40 complex gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation. It also functions cooperatively with the FACT dimer to stimulate elongation by RNA polymerase II. H2BK120Ub also acts as a regulator of mRNA splicing: deubiquitination by USP49 is required for efficient cotranscriptional splicing of a large set of exons.
    Cellular locations: Nucleus. Chromosome.
    Database Links:
  2. Entrez Gene: 10339?Human
  3. Entrez Gene: 10340?Human
  4. Entrez Gene: 337874?Human
  5. Entrez Gene: 440689?Human
  6. Entrez Gene: 54145?Human
  7. Entrez Gene: 8349?Human
  8. Entrez Gene: 104021?Mouse
  9. Entrez Gene: 319190?Mouse
  10. Omim: 601831?Human
  11. SwissProt: O60814?Human
  12. SwissProt: P06899?Human
  13. SwissProt: P23527?Human
  14. SwissProt: P33778?Human
  15. SwissProt: P57053?Human
  16. SwissProt: P58876?Human
  17. SwissProt: P62807?Human
  18. SwissProt: Q16778?Human
  19. SwissProt: Q5QNW6?Human
  20. SwissProt: Q8N257?Human
  21. SwissProt: Q93079?Human
  22. SwissProt: Q99877?Human
  23. SwissProt: Q99879?Human
  24. SwissProt: Q99880?Human
  25. SwissProt: P10854?Mouse
  26. SwissProt: Q64475?Mouse
  27. SwissProt: Q64524?Mouse
  28. Unigene: 473961?Human
  29. Unigene: 632451?Human
    		30.
    Synonyms:
  30. GL105 Antibody
  31. H2B Antibody
  32. H2B 1A Antibody
  33. H2B GL105 Antibody
  34. H2B histone family Antibody
  35. H2B histone family member O Antibody
  36. H2B histone family member Q Antibody
  37. H2B histone family member S Antibody
  38. H2B type 12 Antibody
  39. H2B-GL105 Antibody
  40. H2B.1 Antibody
  41. H2B.1 B Antibody
  42. H2b.1A Antibody
  43. H2B.b Antibody
  44. H2B.c Antibody
  45. H2B.d Antibody
  46. H2B.e Antibody
  47. H2B.f Antibody
  48. H2B.j Antibody
  49. H2B.q Antibody
  50. H2B/a Antibody
  51. H2B/b Antibody
  52. H2B/c Antibody
  53. H2B/d Antibody
  54. H2B/e Antibody
  55. H2B/f Antibody
  56. H2B/g Antibody
  57. H2B/h Antibody
  58. H2B/j Antibody
  59. H2B/l Antibody
  60. H2B/o Antibody
  61. H2B/q Antibody
  62. H2B1_YEAST Antibody
  63. H2B2E_HUMAN Antibody
  64. H2B2f Antibody
  65. H2B2F_HUMAN Antibody
  66. H2Ba Antibody
  67. H2Bf Antibody
  68. H2BFB Antibody
  69. H2BFC Antibody
  70. H2BFD Antibody
  71. H2BFE Antibody
  72. H2BFF Antibody
  73. H2BFJ Antibody
  74. H2BFO Antibody
  75. H2BFQ Antibody
  76. H2BFS Antibody
  77. H2BGL105 Antibody
  78. H2BQ Antibody
  79. HIRIP2 Antibody
  80. HIST1H2BB Antibody
  81. HIST1H2BD Antibody
  82. HIST1H2BH Antibody
  83. HIST1H2BL Antibody
  84. HIST1H2BM Antibody
  85. HIST1H2BN Antibody
  86. HIST2H2BE Antibody
  87. HIST2H2BF Antibody
  88. Histone 2 H2be Antibody
  89. histone cluster 2, H2be Antibody
  90. Histone H2B Antibody
  91. histone H2B GL105 Antibody
  92. histone H2B type 1 Antibody
  93. Histone H2B type 1 B Antibody
  94. Histone H2B type 1 D Antibody
  95. Histone H2B type 1 H Antibody
  96. Histone H2B type 1 L Antibody
  97. Histone H2B type 1 M Antibody
  98. Histone H2B type 1 N Antibody
  99. Histone H2B type 1-B Antibody
  100. Histone H2B type 1-C/E/F/G/I Antibody
  101. Histone H2B type 1-D Antibody
  102. Histone H2B type 1-H Antibody
  103. Histone H2B type 1-L Antibody
  104. Histone H2B type 1-M Antibody
  105. Histone H2B type 1-N Antibody
  106. Histone H2B type 2 E Antibody
  107. Histone H2B type 2-E Antibody
  108. Histone H2B type 2-F Antibody
  109. histone H2B type 2E Antibody
  110. Histone H2B-GL105 Antibody
  111. Histone H2B.1 Antibody
  112. Histone H2B.1 A Antibody
  113. Histone H2B.2 Antibody
  114. Histone H2B.a Antibody
  115. Histone H2B.b Antibody
  116. Histone H2B.f Antibody
  117. Histone H2B.g Antibody
  118. Histone H2B.h Antibody
  119. Histone H2B.k Antibody
  120. Histone H2B.l Antibody
  121. Histone H2B.n Antibody
  122. Histone H2B.q Antibody
  123. histone H2BGL105 Antibody
  124. histone protein Antibody
  125. HTB 1 Antibody
  126. HTB 2 Antibody
  127. HTB1 Antibody
  128. Htb1p Antibody
  129. HTB2 Antibody
  130. Htb2p Antibody
  131. MGC131639 Antibody
  132. SPT 12 Antibody
  133. SPT12 Antibody
  134. Suppressor of Ty protein 12 Antibody
    		135.
    Information: Target information shown above is from the UniProt Consortium.
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