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Anti-CD4 (A429) Antibody |产品详情|进口榴莲视频免费观看采购网


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    Anti-CD4 (A429) Antibody
    品牌：Antibodies
    货号：
    规格：50µl
    货期：

    Anti-CD4 (A429) Antibody
    商品详情 参考文献 相关资料
    Name: Anti-CD4 (A429) Antibody
    See all CD4 primary antibodies
    Description: Rabbit polyclonal antibody to CD4 (A429)
    Specificity: CD4 (A429) pAb detects endogenous levels of CD4 protein.
    Applications: WB, IHC, IF
    Reactivity: Human, Mouse
    Immunogen: Synthetic peptide, corresponding to amino acids 391-440 of Human CD4.
    Host: Rabbit
    Clonality: Polyclonal
    Conjugate: Unconjugated
    Molecular Weight: ~ 51 kDa
    Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
    Product Form: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
    Function: Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
    Post-Translational Modification: Palmitoylation and association with LCK contribute to the enrichment of CD4 in lipid rafts.
    Cellular locations: Cell membrane.

    Localizes to lipid rafts. Removed from plasma membrane by HIV-1 Nef protein that increases clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation. Cell surface expression is also down-modulated by HIV-1 Envelope polyprotein gp160 that interacts with, and sequesters CD4 in the endoplasmic reticulum.
    Database Links:
  2. Entrez Gene: 920?Human
  3. Entrez Gene: 12504?Mouse
  4. Omim: 186940?Human
  5. SwissProt: P01730?Human
  6. SwissProt: P06332?Mouse
  7. Unigene: 631659?Human
  8. Unigene: 2209?Mouse
    		9.
    Synonyms:
  9. CD 4 Antibody
  10. CD4 Antibody
  11. CD4 (L3T4) Antibody
  12. CD4 antigen Antibody
  13. CD4 antigen (p55) Antibody
  14. CD4 molecule Antibody
  15. CD4 receptor Antibody
  16. CD4+ Lymphocyte deficiency, included Antibody
  17. CD4mut Antibody
  18. CD4_HUMAN Antibody
  19. L3T4 Antibody
  20. Leu3 Antibody
  21. Ly-4 Antibody
  22. Lymphocyte antigen CD4 Antibody
  23. MGC165891 Antibody
  24. OTTHUMP00000238897 Antibody
  25. p55 Antibody
  26. T cell antigen T4 Antibody
  27. T cell antigen T4/LEU3 Antibody
  28. T cell differentiation antigen L3T4 Antibody
  29. T cell OKT4 deficiency, included Antibody
  30. T cell surface antigen T4/Leu 3 Antibody
  31. T cell surface antigen T4/Leu3 Antibody
  32. T cell surface glycoprotein CD4 Antibody
  33. T-cell surface antigen T4/Leu-3 Antibody
  34. T-cell surface glycoprotein CD4 Antibody
  35. W3/25 Antibody
  36. W3/25 antigen Antibody
    		37.
    Information: Target information shown above is from the UniProt Consortium.
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