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Anti-CD105 Antibody |产品详情|进口榴莲视频免费观看采购网


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    Anti-CD105 Antibody
    品牌：Antibodies
    货号：
    规格：100T
    货期：

    Anti-CD105 Antibody
    商品详情 参考文献 相关资料
    Name: Anti-CD105 Antibody
    See all CD105 primary antibodies
    Description: Mouse monoclonal (MEM-229) antibody to CD105 (FITC).
    Specificity: The antibody MEM-229 recognizes CD105 (Endoglin), a 90 kDa type I integral membrane homodimer glycoprotein expressed on vascular endothelial cells (small and large vessels), activated monocytes and tissue macrophages, stromal cells of certain tissues including bone marrow, pre-B lymphocytes in fetal marrow and erythroid precursors in fetal and ***** bone marrow; it is also present on syncytiotrophoblast on placenta throughout pregnancy.
    Applications: FC, WB, IHC-Fr, ICC
    Reactivity: Human, Porcine
    Immunogen: Recombinant Vaccinia virus containing the human CD105 (L-isoform) cDNA.
    Host: Mouse
    Clonality: Monoclonal
    Clone: MEM-229
    Isotype: IgG2a
    Conjugate: FITC
    Product Form: Liquid
    Formulation: Supplied in Phosphate Buffered Saline with 15mM Sodium Azide.
    Storage: Store in the dark at 2-8°C. Avoid prolonged exposure to light.
    Function: Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.
    Tissue Specificity: Endoglin is restricted to endothelial cells in all tissues except bone marrow.
    Involvement in Disease: Telangiectasia, hereditary hemorrhagic, 1: A multisystemic vascular dysplasia leading to dilation of permanent blood vessels and arteriovenous malformations of skin, mucosa, and viscera. The disease is characterized by recurrent epistaxis and gastro-intestinal hemorrhage. Visceral involvement includes arteriovenous malformations of the lung, liver, and brain.
    Cellular locations: Membrane.
    Database Links:
  2. Entrez Gene: 2022?Human
  3. Omim: 131195?Human
  4. SwissProt: P17813?Human
  5. Unigene: 76753?Human
    		6.
    Synonyms:
  6. AI528660 Antibody
  7. AI662476 Antibody
  8. CD 105 Antibody
  9. CD105 Antibody
  10. CD105 antigen Antibody
  11. EGLN_HUMAN Antibody
  12. END Antibody
  13. Endoglin Antibody
  14. Eng Antibody
  15. FLJ41744 Antibody
  16. HHT1 Antibody
  17. ORW Antibody
  18. ORW1 Antibody
  19. Osler Rendu Weber syndrome 1 Antibody
  20. RP11 228B15.2 Antibody
  21. S-endoglin Antibody
  22. SN6 Antibody
    		23.
    Information: Target information shown above is from the UniProt Consortium.
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