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Anti-SHP1 Antibody |产品详情|进口榴莲视频免费观看采购网


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    Anti-SHP1 Antibody
    品牌：Antibodies
    货号：
    规格：50µl
    货期：

    Anti-SHP1 Antibody
    商品详情 参考文献 相关资料
    Name: Anti-SHP1 Antibody
    See all SHP1 primary antibodies
    Description: Rabbit monoclonal antibody to SHP1
    Specificity: This antibody detects endogenous levels of SHP1 and does not cross-react with related proteins.
    Applications: WB, ICC/IF, IHC, FC
    Reactivity: Human, Mouse, Rat
    Immunogen: Recombinant antibody.
    Host: Rabbit
    Clonality: Monoclonal
    Conjugate: Unconjugated
    Molecular Weight: ~ 68 kDa
    Purity: Protein A affinity purified
    Product Form: Recombinant Rabbit Monoclonal Antibody. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
    Function: Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
    Tissue Specificity: Isoform 1 is expressed in hematopoietic cells. Isoform 2 is expressed in non-hematopoietic cells.
    Sequence Similarities: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
    Post-Translational Modification: Phosphorylated on tyrosine residues. Binding of KITLG/SCF to KIT increases tyrosine phosphorylation (By similarity). Phosphorylation at Tyr-564 enhances phosphatase activity.
    Cellular locations: Cytoplasm. Nucleus.

    In neurons, translocates into the nucleus after treatment with angiotensin II (By similarity). Shuttles between the cytoplasm and nucleus via its association with PDPK1.
    Database Links:
  2. Entrez Gene: 5777?Human
  3. Entrez Gene: 15170?Mouse
  4. Entrez Gene: 116689?Rat
  5. Omim: 176883?Human
  6. SwissProt: P29350?Human
  7. SwissProt: P29351?Mouse
  8. SwissProt: P81718?Rat
  9. Unigene: 63489?Human
  10. Unigene: 271799?Mouse
  11. Unigene: 18985?Rat
    		12.
    Synonyms:
  12. 70Z-SHP Antibody
  13. EC 3.1.3.48 Antibody
  14. HCP Antibody
  15. HCPH Antibody
  16. Hematopoietic cell phosphatase Antibody
  17. Hematopoietic cell protein tyrosine phosphatase Antibody
  18. Hematopoietic cell protein-tyrosine phosphatase Antibody
  19. HPTP1C Antibody
  20. Protein tyrosine phosphatase 1C Antibody
  21. Protein tyrosine phosphatase non receptor type 6 Antibody
  22. Protein tyrosine phosphatase SHP1 Antibody
  23. Protein-tyrosine phosphatase 1C Antibody
  24. protein-tyrosine phosphatase SHP 1 Antibody
  25. Protein-tyrosine phosphatase SHP-1 Antibody
  26. PTN6_HUMAN Antibody
  27. PTP 1C Antibody
  28. PTP-1C Antibody
  29. PTP1C Antibody
  30. Ptpn6 Antibody
  31. SH PTP 1 Antibody
  32. SH PTP1 Antibody
  33. SH-PTP1 Antibody
  34. SHP 1 Antibody
  35. SHP 1L Antibody
  36. SHP1 Antibody
  37. SHP1L Antibody
  38. tyrosine protein phosphatase non receptor type 6 Antibody
  39. Tyrosine-protein phosphatase non-receptor type 6 Antibody
    		40.
    Information: Target information shown above is from the UniProt Consortium.
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