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Anti-AIMP1 Antibody |产品详情|进口榴莲视频免费观看采购网





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    Anti-AIMP1 Antibody
    品牌:Antibodies
    货号:
    规格:50µl
    货期:

    Anti-AIMP1 Antibody

    商品详情 参考文献 相关资料
    Name: Anti-AIMP1 Antibody
    See all AIMP1 primary antibodies
    Description: Rabbit polyclonal antibody to AIMP1.
    Applications: WB, IHC, IF
    Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200.
    Reactivity: Human, Mouse, Rat
    Immunogen: Recombinant protein of human AIMP1.
    Protein Length: 312 (336)
    Host: Rabbit
    Clonality: Polyclonal
    Isotype: IgG
    Conjugate: Unconjugated
    Purification: Affinity purification.
    Product Form: Liquid
    Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
    Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
    Function: Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7.
    Involvement in Disease: Leukodystrophy, hypomyelinating, 3: A severe autosomal recessive hypomyelinating leukodystrophy characterized by early infantile onset of global developmental delay, lack of development, lack of speech acquisition, and peripheral spasticity associated with decreased myelination in the central nervous system.
    Post-Translational Modification: Cleaved by caspase-7 in response to apoptosis to produce EMAP-II.
    Cellular locations: Nucleus. Cytoplasm > Cytosol. Cytoplasmic vesicle > Secretory vesicle. Secreted. Endoplasmic reticulum. Golgi apparatus.

    Enriched in secretory vesicles of pancreatic alpha cells and secreted from the pancreas in response to low glucose levels (By similarity). Also secreted in response to hypoxia and both apoptotic and necrotic cell death.
    Database Links:
  1. Entrez Gene: 9255?Human
  2. Entrez Gene: 13722?Mouse
  3. Entrez Gene: 114632?Rat
  4. Omim: 603605?Human
  5. SwissProt: Q12904?Human
  6. SwissProt: P31230?Mouse
  7. Unigene: 591680?Human
  8. Unigene: 235137?Mouse
  9. Synonyms:
  10. AIMP 1 Antibody
  11. Aimp1 Antibody
  12. AIMP1/p43 Antibody
  13. AIMP1_HUMAN Antibody
  14. Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 Antibody
  15. ARS interacting multifunctional protein 1 Antibody
  16. EMAP 2 Antibody
  17. EMAP II Antibody
  18. EMAP-2 Antibody
  19. EMAP-II Antibody
  20. EMAP2 Antibody
  21. EMAPII Antibody
  22. Endothelial monocyte activating polypeptide Antibody
  23. Endothelial monocyte activating polypeptide 2 Antibody
  24. Endothelial monocyte-activating polypeptide 2 Antibody
  25. Endothelial monocyte-activating polypeptide II Antibody
  26. HLD3 Antibody
  27. Multisynthase complex auxiliary component p43 Antibody
  28. Multisynthetase complex auxiliary component p43 Antibody
  29. OTTHUMP00000219673 Antibody
  30. p43 Antibody
  31. Scye 1 Antibody
  32. Scye1 Antibody
  33. Scye1, formerly Antibody
  34. Small inducible cytokine subfamily E member 1 Antibody
  35. Small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) Antibody
  36. Small inducible cytokine subfamily E, member 1, formerly Antibody
  37. Information: Target information shown above is from the UniProt Consortium.
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