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Anti-Fibronectin 1 (F2372) Antibody |产品详情|进口榴莲视频免费观看采购网





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    Anti-Fibronectin 1 (F2372) Antibody
    品牌:Antibodies
    货号:
    规格:50µl
    货期:

    Anti-Fibronectin 1 (F2372) Antibody

    商品详情 参考文献 相关资料
    Name: Anti-Fibronectin 1 (F2372) Antibody
    See all Fibronectin 1 primary antibodies
    Description: Rabbit polyclonal antibody to Fibronectin 1 (F2372)
    Specificity: Fibronectin 1 (F2372) pAb detects endogenous levels of Fibronectin 1 protein.
    Applications: WB, IHC
    Reactivity: Human, Mouse, Rat
    Immunogen: Synthetic peptide, corresponding to amino acids 2331-2380 of Human Fibronectin 1.
    Host: Rabbit
    Clonality: Polyclonal
    Conjugate: Unconjugated
    Molecular Weight: ~ 260 kDa
    Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
    Product Form: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
    Function: Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.
    Tissue Specificity: Plasma FN (soluble dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. Ugl-Y1, Ugl-Y2 and Ugl-Y3 are found in urine.
    Involvement in Disease: Glomerulopathy with fibronectin deposits 2: Genetically heterogeneous autosomal dominant disorder characterized clinically by proteinuria, microscopic hematuria, and hypertension that leads to end-stage renal failure in the second to fifth decade of life.
    Post-Translational Modification: Sulfated.
    Cellular locations: Secreted > Extracellular space > Extracellular matrix.
    Database Links:
  1. Entrez Gene: 2335?Human
  2. Entrez Gene: 14268?Mouse
  3. Entrez Gene: 25661?Rat
  4. Omim: 135600?Human
  5. SwissProt: P02751?Human
  6. SwissProt: P11276?Mouse
  7. SwissProt: P04937?Rat
  8. Unigene: 203717?Human
  9. Unigene: 193099?Mouse
  10. Unigene: 1604?Rat
  11. Synonyms:
  12. CIG Antibody
  13. Cold insoluble globulin Antibody
  14. Cold-insoluble globulin Antibody
  15. DKFZp686F10164 Antibody
  16. DKFZp686H0342 Antibody
  17. DKFZp686I1370 Antibody
  18. DKFZp686O13149 Antibody
  19. ED B Antibody
  20. Fibronectin Antibody
  21. Fibronectin 1 Antibody
  22. FINC Antibody
  23. FINC_HUMAN Antibody
  24. FN Antibody
  25. FN1 Antibody
  26. FNZ Antibody
  27. GFND Antibody
  28. GFND2 Antibody
  29. LETS Antibody
  30. Migration stimulating factor Antibody
  31. MSF Antibody
  32. Ugl-Y3 Antibody
  33. Information: Target information shown above is from the UniProt Consortium.
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