Anti-CD63 Antibody |产品详情|进口榴莲视频免费观看采购网

您好，欢迎来到榴莲视频下载地址入口生物网站！请登录注册

我的订单 | 联系榴莲视频下载地址入口 | 在线客服QQ：3012681483 | 客服电话：400-968-7988 | 工作时间：08:30-17:30

主营产品： ELISA8008APP幸福宝榴莲、抗体、补体血清、兔补体、干扰素、小鼠测温仪、进口榴莲视频免费观看、Quidel代理、Swant代理、PBL Assay Science代理

网站首页产品中心代理品牌新闻资讯资源中心关于榴莲视频下载地址入口

所在位置：首页 > 产品中心 > Antibodies > Antibodies产品

订购信息

上海榴莲视频下载地址入口生物科技公司

Tel:400-968-7988 021-33779008

Anti-CD63 Antibody

品牌：Antibodies

货号：

规格：100µg

货期：

应用：

咨询客服

立即购买加入购物车

Anti-CD63 Antibody

商品详情参考文献相关资料

Overview

Name:	Anti-CD63 Antibody See all CD63 primary antibodies
Description:	Mouse monoclonal (MEM-259) antibody to CD63.
Specificity:	The antibody MEM-259 reacts with CD63 (LAMP-3), a 40-60 kDa tetraspan glycoprotein expressed by granulocytes, platelets, T cells, monocytes/macrophages and endothelial cells. Cell surface exposition of CD63 is usually activation-dependent.
Applications:	FC, IP, IHC-P, ICC
Reactivity:	Human
Immunogen:	HPB-ALL T cell line.
Host:	Mouse
Clonality:	Monoclonal
Clone:	MEM-259
Isotype:	IgG1
Conjugate:	Unconjugated
Purification:	Protein A chromatography.
Concentration:	1 mg/ml
Purity:	> 95% (by SDS-PAGE)
Product Form:	Liquid
Formulation:	Supplied in Phosphate Buffered Saline, pH 7.4, with 15mM Sodium Azide.
Storage:	Store at 2-8°C.

Target

Function:	Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.
Tissue Specificity:	Detected in platelets (at protein level). Dysplastic nevi, radial growth phase primary melanomas, hematopoietic cells, tissue macrophages.
Sequence Similarities:	Belongs to the tetraspanin (TM4SF) family.
Post-Translational Modification:	Palmitoylated at a low, basal level in unstimulated platelets. The level of palmitoylation increases when platelets are activated by thrombin (in vitro).
Cellular locations:	Cell membrane. Lysosome membrane. Late endosome membrane. Endosome > Multivesicular body. Melanosome. Secreted > Exosome. Cell surface. Also found in Weibel-Palade bodies of endothelial cells (PubMed:10793155). Located in platelet dense granules (PubMed:7682577). Detected in a subset of pre-melanosomes. Detected on intralumenal vesicles (ILVs) within multivesicular bodies (PubMed:21962903).
Database Links:	Entrez Gene: 967?Human Omim: 155740?Human SwissProt: P08962?Human Unigene: 445570?Human
Synonyms:	Lysosomal associated membrane protein 3 Antibody CD 63 Antibody CD63 Antibody CD63 antigen Antibody CD63 antigen (melanoma 1 antigen) Antibody CD63 antigen melanoma 1 antigen Antibody CD63 molecule Antibody CD63_HUMAN Antibody gp55 Antibody Granulophysin Antibody LAMP 3 Antibody LAMP-3 Antibody LAMP3 Antibody LIMP Antibody Lysosomal-associated membrane protein 3 Antibody Lysosome associated membrane glycoprotein 3 Antibody Mast cell antigen AD1 Antibody ME491 Antibody Melanoma 1 antigen Antibody Melanoma associated antigen ME491 Antibody Melanoma associated antigen MLA1 Antibody Melanoma-associated antigen ME491 Antibody MGC72893 Antibody MLA 1 Antibody MLA1 Antibody NGA Antibody Ocular melanoma associated antigen Antibody Ocular melanoma-associated antigen Antibody OMA81H Antibody PTLGP40 Antibody Tetraspanin 30 Antibody Tetraspanin-30 Antibody Tspan 30 Antibody Tspan-30 Antibody TSPAN30 Antibody
Information:	Target information shown above is from the UniProt Consortium.